CCL2 modulates cytokine production in cultured mouse astrocytes
نویسندگان
چکیده
منابع مشابه
Activation of Protease-Activated Receptor 2-Mediated Signaling by Mast Cell Tryptase Modulates Cytokine Production in Primary Cultured Astrocytes
Protease-activated receptor 2 (PAR-2), which is abundantly expressed in astrocytes, is known to play major roles in brain inflammation. However, the influence of the natural agonist of PAR-2, tryptase, on proinflammatory mediator releasedfrom astrocytes remains uninvestigated. In the present study, we found that tryptase at lower concentrations modestly reduced intracellular ROS production but ...
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ژورنال
عنوان ژورنال: Journal of Neuroinflammation
سال: 2010
ISSN: 1742-2094
DOI: 10.1186/1742-2094-7-67